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Horse Chestnut (Aesculus, Buckeye, Spanish Chestnut)
Aesculus hippocastanum |
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Active
constituents include: |
Saponin – aescin, flavonoids, sterols, tannins, and coumarins |
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Proposed
use: |
Varicose veins, improving venous return, haemorrhoids, phlebitis, prostatic hypertrophy |
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Contraindications: |
CI: Renal or hepatic impairment, pregnancy and breast feeding
W: Interaction with anti-coagulant therapy |
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Renal
specific warnings: |
At high doses renal toxicity (effects tubular transport processes |
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Adverse
effects: |
High doses renal and hepatic toxicity, relatively safe at recommended doses. Haemolysis in overdose, allergic dermatitis |
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Pharmacological
properties: |
Human: Double-blind, controlled trials have showed significant benefit for peripheral oedema probably by a decrease in trans-capillary filtration by stabilizing the lysosomal membrane.
Animal: Anti-inflammatory, analgesic and anti-granulation effects reported. |
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Quality
of available information: |
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Legal
Category if available: |
GSL (external use only) |
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Further
information: |
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Date
of Monograph: |
06 June 2001 |
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The information
provided is based on the current literature and evidence avialable.
For some herbs, there is little information available and
the evidence of side effects is anecdotal. However, we are
endeavouring to update and improve the quality of information
all the time. We advice you to discuss taking any herbal medicines
with a person who specialises in this field.
Nephronline
or the authors cannot take any responsibility for any adverse
effects from the use of these herbs.
References:
- Newall,
C., Anderson, L. & Phillipson. J.D. (1996). Herbal Medicines:
A guide for health-care professionals. London: The Pharmaceutical
Press.
- Mills,
S. & Bone, K. (2000). Principles and practice of Phytotherapy.
Modern herbal medicine. Edinburgh: Churchill Livingstone.
Web
sites to check out:
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