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so -- you're having a biopsy!
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This leaflet is designed to answer any questions you may have about your biopsy. But if you are still unsure about anything, please ask your doctor or a nurse.
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What is a biopsy?

A biopsy is the removal of a small piece of tissue from an organ of the body, in your case one of your kidneys. When kidneys stop working properly, doctors need to find out why. Sometimes this can only be done by taking a small specimen of tissue from kidneys and looking at it to see if it can show what is causing the kidney failure. The tissue removed will be examined under a microscope in a laboratory, to help the doctors diagnose your condition.

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When will I be told the result?
It takes 10 days for a complete report to be compiled. Usually, you will be given an Out-Patient Clinic appointment for two weeks after the biopsy to discuss the results. However, if you are an In Patient, a provisional report may be available within one or two days.

What happens before a Renal Biopsy?
Before the procedure can begin, the medical team will make sure that it is safe to proceed. Your blood pressure will be checked and blood samples taken. These tests will tell the team how well your kidneys are working, and help them to be sure that there is only the smallest risk of any bleeding after the biopsy has been performed. You will be asked for your consent to the biopsy, and the risks will be explained to you before you give that consent. It is advisable to eat only a light meal before the procedure. You will be asked to wear a Theatre gown and to empty your bladder.

What are the risks of a renal biopsy?
Any medical or surgical procedure carries risks. The main one associated with a renal biopsy is bleeding in the kidney, but this complication is rare. You are only being asked to undergo this procedure because your doctor believes that the risks are outweighed by the benefits. All possible precautions will be taken to prevent bleeding. If it does occur, you will be observed closely and treated accordingly. You will not be discharged until it is safe to do so.

What happens during the biopsy?
Biopsies are usually done in either the Renal Unit or the X-ray Department. You will be asked to lie on your front with a hard pillow under your stomach. This allows the doctor easier access to the kidneys, which are situated in the back of your abdomen on either side. The position of the kidneys is then checked using an ultrasound scan.

When the doctor is ready to begin, an antiseptic solution is used to clean your skin. Green towels are then draped to surround the sterile area this creates and an injection of local anaesthetic is given. It takes a little while for the local anaesthetic to work.

When the area is numb you will be asked to hold your breath and keep still. At this moment a special biopsy needle will be introduced through the skin into the kidney to take the small sample. Only one kidney will be sampled. This part of the procedure is very quick, but may have to be repeated more than once to get enough tissue for analysis.

What happens immediately after the biopsy?
Once the sample has been taken, a small dressing is applied to the biopsy site. You will then be asked to lie flat for four hours and you will remain "on bed rest" for 24 hours after your biopsy time. Your blood pressure and pulse will be monitored frequently and the dressing checked to make sure that everything is well.

Some people see blood in their urine after a biopsy. This is not unusual and not a cause for concern. However, it will be closely monitored by the nursing staff. Your discharge is normally planned for the day after the procedure.

What happens in the days following the biopsy?
Once home, you should rest and take it easy for one week. It is not unusual to get discomfort from around the biopsy site during the first week. Paracetamol taken regularly will ease this discomfort.

After the first week, there should be no reason why you cannot resume your normal activities. However, if you experience dizziness, visible blood in your urine or severe pain, please contact the Renal Unit at once.

This leaflet has been prepared by Martin Hague, Vascular Access Trainer, and Alison Smith, Director of Nursing, Sheffield Kidney Institute. There maybe local variations in practice please speak to your local health care team for specific information.

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